公共卫生学院环境卫生与毒理学系讲师。基于多种模式动物（秀丽隐杆线虫、小鼠等），开展环境因素（环境污染物、辐射等）诱发代谢综合征和跨代毒性的健康效应评估，以及分子机制探究。以第一作者（含共一第一）发表毒理学领域SCI论文共6篇。
电子邮箱：wmhee2026@wmu.edu.cn
一、研究方向（不超过3个） |
1. 环境因素与代谢综合征发病及机制探究； 2. 环境因素的跨代效应及表观遗传机制探究； 3. 基于多种模型的毒理学评价。 |
二、教学育人成果 |
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三、科研项目 |
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四、发表论文（具有代表性的5篇） |
1. He W, Chen X, Zhou S, Fu Z, Xu J, Liu Q, Cubero FJ, Li Z, Zhou Y, Wang D, Jiang G, Gu A. Bisphenol S Induced Transgenerational Lipid Accumulation by Triggering Intestine-to-Germline Histone H3K4me3 Modification in Caenorhabditis elegans. Environ Sci Technol. 2025 Jul 29;59(29):14957-14968. 2. He W, Gu A, Wang D. Four-week repeated exposure to tire-derived 6-PPD quinone causes multiple organ injury in male BALB/c mice. Sci Total Environ. 2023 Oct 10;894:164842. 3. He W, Chao J, Gu A, Wang D. Evaluation of 6-PPD quinone toxicity on lung of male BALB/c mice by quantitative proteomics. Sci Total Environ. 2024 Apr 20;922:171220. 4. He W, Liu Z, Zhang H, Liu Q, Weng Z, Wang D, Gu A. Bisphenol S decreased lifespan and healthspan via insulin/IGF-1-like signaling-against mitochondrial stress in Caenorhabditis elegans. Ecotoxicol Environ Safe. 2024 Oct 15;285:117136. 5. He W, Gu A, Wang D. Sulfonate-Modified Polystyrene Nanoparticle at Precited Environmental Concentrations Induces Transgenerational Toxicity Associated with Increase in Germline Notch Signal of Caenorhabditis elegans. Toxics. 2023 Jun 6;11(6):511. |
五、所获科研成果 |
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